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Cancer Vaccines
Data on cancer vaccines detailed by researchers at Osaka University
August 26th, 2008
New research, 'WT1 peptide vaccine for the treatment of cancer,' is the subject of a report. According to recent research from Japan, "Wilms' tumor gene WT1 is expressed in various kinds of cancers. Human WT1-specific cytotoxic T lymphocytes (CTLs) were generated, and mice immunized with WT1 peptide rejected challenges by WT1-expressing cancer cells without auto-aggression to normal organs." "Furthermore, WT1 antibodies and WT1-specific CTLs were detected in cancer patients, indicating that WT1 protein was immunogenic. These findings provided us with the rationale for cancer immunotherapy targeting WT1. Clinical trials of WT1 peptide vaccination for cancer patients were...
Source: Cancer Weekly (2008-08-26)
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