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Cancer Weekly

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Angiogenesis



Scientists at University of Ulsan detail research in angiogenesis



August 26th, 2008

In this recent report, researchers in Seoul, South Korea conducted a study "To evaluate the potential effect of bevacizumab, a monoclonal antibody against vascular endothelial growth factor (VEGF), on the angiogenesis and tumor growth of retinoblastoma in vitro and in vivo. The antiangiogenic effects of bevacizumab were evaluated in a coculture of a Y-79 human retinoblastoma cell line and a human umbilical vein endothelial cell line by means of a cell proliferation assay kit and a VEGF enzyme-linked immunosorbent assay."

"The Y-79 xenotransplanted nude mice were treated with bevacizumab intraperitoneally twice weekly for 4 weeks, during which each tumor was measured...


Source: Cancer Weekly (2008-08-26)

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