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Cancer Weekly

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Cancer Gene Therapy



Investigators at Okayama University publish new data on cancer gene therapy



September 2nd, 2008

Fresh data on cancer gene therapy are presented in the report 'M-RIP, a novel target of JNK signaling and a requirement for human cancer cell invasion.' According to a study from Okayama, Japan, "Cell motility is involved in physiological and pathological processes such as the invasion and migration of cells. c-Jun N-terminal kinase (JNK) cascades are involved in the invasion and metastasis of cancer cells. However, little is known about the downstream signaling of JNK."

"In the present study, we used small interfering RNA (siRNA) directed against JNK1 to reduce its expression. We used microarray techniques to compare the gene expression profiles of epidermal growth...


Source: Cancer Weekly (2008-09-02)

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