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Gene Therapy
Data on gene therapy reported by researchers at Guangzhou Medical College, Department of Surgery
September 2nd, 2008
Fresh data on gene therapy are presented in the report 'Transfection of the DAAO gene and subsequent induction of cytotoxic oxidative stress by D-alanine in 9L cells.' "D-amino acid oxidase (DAAO) can catalyze the dehydrogenation of D-amino acids, such as D-alanine, to the corresponding amino acids and is then reoxidized by molecular oxygen to yield hydrogen peroxide, a reactive oxygen species, which reacts with DNA, lipids and protein, inducing cell death. This study investigated whether rat glioma 9L cells infected with the recombinant retrovirus containing the DAAO cDNA fragment can be induced in order to undergo cytotoxic oxidative stress by D-alanine," researchers in Guangzhou,...
Source: Cancer Weekly (2008-09-02)
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