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Colon Cancer

Findings from Kyushu University in colon cancer reported

Published in Cancer Weekly, September 2nd, 2008

"Human platelet-derived growth factor BB (PDGF-BB) is thought to be involved in human malignancies. Its overexpression has been reported in some human tumors," scientists writing in the journal Annals of Surgical Oncology report.

"However, its expression in colorectal cancer has not been studied. We thus investigated the clinicopathological and biological significance of PDGF-BB gene expression in human colorectal cancer. Using real-time reverse transcription-PCR, we evaluated PDGF-BB expression status and correlated data with clinicopathological parameters in 60 patients with colorectal cancer. Additionally, we established a colorectal cancer cell line...

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