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Cancer Weekly

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Reovirus Therapy



Data on reovirus therapy described by researchers at Institute of Hematology and Blood Transfusion



September 2nd, 2008

Investigators publish new data in the report 'Efficacy of reovirus therapy combined with cyclophosphamide and gene-modified cell vaccines on tumors induced in mice by HPV16-transformed cells.' "Oncolytic virotherapy is a novel approach to cancer treatment. In the present study we tested the ability of reovirus type 3, strain Dearing, to suppress the growth of tumors induced in mice by HPV16-transformed TC-1 cells," scientists in Prague, Czech Republic report.

"In vitro, these cells are highly susceptible to the virus. In repeated in vivo tests the intratumoral inoculation of the virus resulted in only a minor slow-down of tumor growth, never in a complete cure. The...


Source: Cancer Weekly (2008-09-02)

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