Prostate Cancer
Studies from H.C. Whitaker et al in the area of prostate cancer described
Published in Cancer Weekly, September 2nd, 2008
"Wnt signaling is thought to be important in prostate cancer, in part because proteins such as beta-catenin can also affect androgen receptor signaling. beta-Catenin forms a cell adhesion complex with E-cadherin raising the possibility that loss of expression or a change in beta-catenin distribution in the cell could also alter downstream signaling, decreased inter-cellular adhesion and the promotion of metastasis. A number of studies have reported the altered expression and/or localization of beta-catenin as a biomarker in prostate cancer," scientists writing in the journal Prostate report.
"Tissue microarrays comprised of BPH and low, moderate and high-grade...
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Source: Cancer Weekly (2008-09-02)
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