Breast Cancer
Findings from C.B. Nunes et al in breast cancer reported
Published in Cancer Weekly, September 2nd, 2008
In this recent report, researchers in Belo Horizonte, Brazil conducted a study "To compare the sensitivity and specificity of new rabbit monoclonal antibody SP3 with those of mouse monoclonal and rabbit polyclonal antibodies using HER2 amplification defined by chromogenic in situ hybridisation (CISH) as the gold standard. Serial sections from tissue microarrays (TMAs) containing 84 breast carcinomas were submitted to CISH (Zymed HER2 Spot- Light kit) and immunohistochemistry, using NeoMarkers SP3 (rabbit monoclonal), DAKO A0485 and DAKO Hercep Test (polyclonal), Novocastra NCL-CB11, Cell Marque CM-CB11, and Genentech 4D5 (mouse monoclonal)."
"The best antibody...
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Source: Cancer Weekly (2008-09-02)
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