Cancer Weekly
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Cancer Vaccines
New cancer vaccines research reported from Emory University
September 2nd, 2008
"Follicular lymphoma (FL) is a common indolent lymphoma associated with a relapsing course. Preclinical models and clinical studies demonstrate that immunizing FL patients against their own tumor idiotype induces humoral and cellular immunity and supresses tumor growth," scientists writing in the journal Expert Opinion on Biological Therapy report. "We review idiotype vaccine strategies that have been tested in FL patients in frontline and relapsed settings to examine the safety and efficacy of this approach. Several Phase II trials of recombinant or hybridoma-produced vaccines or vaccines combined with other immunotherapy demonstrate cellular and humoral...
Source: Cancer Weekly (2008-09-02)
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