Cancer Weekly
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Cancer Vaccines
Studies from Johns Hopkins University, Medical Department have provided new data on cancer vaccines
September 2nd, 2008
"There is an urgent need to develop new innovative therapies for the control of cancer. Antigen-specific immunotherapy and the employment of proteasome inhibitors have emerged as two potentially plausible approaches for the control of cancer," scientists in the United States report. "In the current study, we explored the combination of the DNA vaccine encoding calreticulin (CRT) linked to human papillomavirus type 16 E7 antigen (CRT/E7) with the proteasome inhibitor, bortezomib, for their ability to generate E7-specific immune responses and antitumor effects in vaccinated mice. We found that the combination of treatment with bortezomib and CRT/E7(detox) DNA generated...
Source: Cancer Weekly (2008-09-02)
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