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Cancer Weekly

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Neuroblastoma



Gene That Causes Childhood Cancer Neuroblastoma Is Found



September 9th, 2008

Scientists have discovered gene mutations that are the main cause of the inherited version of the childhood cancer neuroblastoma. In addition, the researchers found that the same mutations play a significant role in high-risk forms of non-inherited neuroblastoma, the more common form of the disease.

"This discovery enables us to offer the first genetic tests to families affected by the inherited form of this disease," said pediatric oncologist Yael P. Mosse, M.D., of The Children's Hospital of Philadelphia, the first author of the study, published online Aug. 24 in the journal Nature. "Furthermore, because there already are drugs in development that target the same gene...


Source: Cancer Weekly (2008-09-09)

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