Cancer Weekly
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Angiogenesis
Reports from R.T. Lee and colleagues advance knowledge in angiogenesis
September 9th, 2008
According to recent research from the United States, "The ability of cancer cells to promote angiogenesis has been associated with a transition from a micrometastatic phenotype to a state in which large solid metastases can form. We describe a case of metastatic melanoma that presented with large numbers of circulating tumor cells and tissue infiltration without large solid metastases." "Immunohistochemistry and reverse transcriptase-PCR was used to study the expression of melanoma tumor markers in circulating tumor cells. A tumor cell line was established from the patient and analyzed for adhesion molecule expression, expression of vascular endothelial growth factor,...
Source: Cancer Weekly (2008-09-09)
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