Soft Tissue Sarcoma Therapy

University of Texas, M. D. Anderson Cancer Center details research in soft tissue sarcoma therapy

Published in Cancer Weekly, September 9th, 2008

Investigators publish new data in the report 'Midkine enhances soft-tissue sarcoma growth: a possible novel therapeutic target.' "New therapeutic targets for soft-tissue sarcoma (STS) treatment are critically needed. Midkine (MK), a multifunctional cytokine, is expressed during midgestation but is highly restricted in normal adult tissues," researchers in the United States report.

"Renewed MK expression was shown in several malignancies where protumorigenic properties were described. We evaluated the expression and function of MK in STS. Immunohistochemistry, reverse transcription-PCR, and Western blotting (WB) evaluated MK expression in human STS tissues and cell...

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Source: Cancer Weekly (2008-09-09)

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