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Cancer Weekly

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Mary Ann Liebert, Inc



Previous Claims of siRNA Therapeutic Effects Called into Question by Report in 'Human Gene Therapy'



September 16th, 2008

The many recent reports documenting the therapeutic efficacy of short interfering RNAs (siRNAs) in animal models of human disease may actually be describing non-specific therapeutic effects related to the ability of siRNA to activate an immune response, according to a paper in the September 2008 issue (Volume 19, Number 9) of 'Human Gene Therapy,' a peer-reviewed journal published by Mary Ann Liebert, Inc. The paper, which was published "instant online," is available free online at www.liebertpub.com/hum

Marjorie Robbins, Adam Judge, Ellen Ambegia, Catherine Choi, Ed Yaworski, Lorne Palmer, Kevin McClintock, and Ian MacLachaln of Protiva Biotherapeutics (Burnaby, BC...


Source: Cancer Weekly (2008-09-16)

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