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Myeloma
Human Genome Sciences Reports Initial Results of Randomized Phase 2 Trial of HGS-ETR1 in Combination With Bortezomib in Advanced Multiple Myeloma
September 16th, 2008
Human Genome Sciences, Inc. (NASDAQ:HGSI) reported initial topline results from an ongoing randomized Phase 2 clinical trial of its TRAIL receptor antibody HGS-ETR1 (mapatumumab) in combination with bortezomib (Velcade) in patients with advanced multiple myeloma. The initial data from the multiple myeloma study show that HGS-ETR1 was well tolerated and suggest that disease response was comparable for this combination vs. bortezomib alone. "We continue to be excited about HGS-ETR1 and our TRAIL receptor antibody program," said David C. Stump, M.D., Executive Vice President, Research and Development, HGS. "The TRAIL-mediated apoptosis pathway is an important area of...
Source: Cancer Weekly (2008-09-16)
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