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Cancer Weekly

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Cancer Gene Therapy



Researchers from University Medical Center report recent findings in cancer gene therapy



September 16th, 2008

New investigation results, 'Improved tumor targeting of anti-epidermal growth factor receptor Nanobodies through albumin binding: taking advantage of modular Nanobody technology,' are detailed in a study published in Molecular Cancer Therapeutics. According to recent research from Amsterdam, Netherlands, "The approximately 15-kDa variable domains of camelid heavy-chain-only antibodies (called Nanobodies) can easily be formatted as multivalent or multispecific single-chain proteins. Because of fast excretion, however, they are less suitable for therapy of cancer."

"In this study, we aimed for improved tumor targeting of a bivalent anti-epidermal growth factor...


Source: Cancer Weekly (2008-09-16)

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