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Gene Therapy
Study findings from Nantong University, Department of Pathology provide new insights into gene therapy
September 16th, 2008
New research, 'Mutant p27(Kip1) and its potential effect as hepatocellular gene therapy,' is the subject of a report. "The cyclin-dependent kinase (cdk) inhibitor p27(Kip1) is an important regulator of cell cycle progression as it negatively regulates G(0/1) progression and plays a major role in controlling the cell cycle. The screening of the p27(Kip1) sequence identified many potential phosphorylation sites," scientists writing in the journal Archives of Medical Research report. "To investigate the effects of the overexpression of exogenous p27(Kip1) protein lacking the Thr157 sites on subcellular localization, cell cycle, and proliferation, a plasmid was...
Source: Cancer Weekly (2008-09-16)
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