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Cancer Weekly

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Angiogenesis



New angiogenesis study results from Sichuan University described



September 16th, 2008

"The number of blood vessels correlates with metastasis in solid tumors, including oral squamous cell carcinoma (OSCC). Hypoxia inducible factor-1alpha (HIF-1 alpha) could play a role in tumor lymphangiogenesis by regulating the lymphatic expression of vascular endothelial growth factor-C (VEGF-C)," scientists in Chengdu, People's Republic of China report.

"HIF-1 alpha protein expression, VEGF-C protein expression, lymphatic vessel density (LVD) and blood vessel density (BVD) in OSCC were investigated. HIF-1 alpha and VEGF-C protein expression were investigated by means of immunohistochemistry in samples from 65 cases of OSCC. The density of the lymphatic microvessels...


Source: Cancer Weekly (2008-09-16)

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