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Cancer Weekly

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Angiogenesis



Recent findings from L.M. Weisenthal and co-authors highlight research in angiogenesis



September 16th, 2008

"Angiogenesis studies are limited by the clinical relevance of laboratory model systems. We developed a new method for measuring dead microvascular (MV) cells in clinical tissue, fluid and blood specimens, and applied this system to make several potentially novel observations relating to cancer pharmacology," scientists writing in the Journal of Internal Medicine report.

"Dead MV cells tend to have a hyperchromatic, refractile quality, further enhanced during the process of staining with Fast Green and counterstaining with either haematoxylin-eosin or Wright-Giemsa. We used this system to quantify the relative degree of direct antitumour versus anti-MV effects of...


Source: Cancer Weekly (2008-09-16)

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