Cancer Weekly
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Angiogenesis
Researchers from University of Freiburg provide details of new studies and findings in the area of angiogenesis
September 16th, 2008
"Recent studies have challenged the previously postulated concept of a tumor-suppressive effect of carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM-1). A possible angiogenic influence of CEACAM-1 in non-small-cell Lung cancer (NSCLC) has not been investigated so far," investigators in Freiburg, Germany report. "Therefore, we examined microvessel density (MVD) and CEACAM-1 expression in primary NSCLC and analyzed their possible correlations under consideration of their prognostic effects. Specimens from 82 consecutive patients with completely resected NSCLC were stained immunohistochemically using the monoclonal anti-CEACAM-1 antibody 4D1 /C2 and the...
Source: Cancer Weekly (2008-09-16)
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