Cancer Weekly
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Apoptosis
Studies from L. Mandoky and co-researchers in the area of apoptosis published
September 16th, 2008
"Cisplatin-based chemotherapy can cure more than 80% of metastatic germ cell testicular tumors (GCT). Germ cells are particularly susceptible to apoptosis and it is reasonable to presume that GCTs are curable because of an intact and effective apoptotic pathway," scientists writing in the journal Anticancer Research report. "The expression of p53 and p21 was investigated in conjunction with the spontaneous apoptotic index in 20 refractory and 50 chemosensitive GCTs, with a complete follow-up. To detect a differentiation-dependent alteration in the apoptotic pathway, all of the histological tumor types were examined separately. Embryonal carcinoma components...
Source: Cancer Weekly (2008-09-16)
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