Cancer Weekly
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Gene Therapy
Report summarizes gene therapy study findings from I.A.W. Ho and co-researchers
September 23rd, 2008
According to recent research from Singapore, Singapore, "Human bone marrow-derived mesenchymal stem cells (BM-hMSCs) are nonhematopoietic stem cells that have the potential to differentiate into adipocytes, osteocytes and chondrocytes. Because of its propensity to migrate to the sites of injury and the ability to expand them rapidly, BM-hMSCs have been exploited as potential gene transfer vehicles to deliver therapeutic genes." "Herein, we evaluated the feasibility of employing herpes simplex virus type 1 (HSV-1) amplicon viral vector as a gene delivery vector to BM-hMSCs. High transduction efficiencies were consistently observed in different isolates of BM-hMSCs...
Source: Cancer Weekly (2008-09-23)
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