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Cancer Weekly

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Helicobacter



Researchers from University of Tartu report recent findings in helicobacter



September 23rd, 2008

According to a study from Ravila, Estonia, "Helicobacter pylori infection causes chronic gastritis, peptic ulcer, and gastric cancer. Colonization of H. pylori in the stomach activates Toll-like and Nod-like receptors to induce not only innate immunity but also adaptive Th1 responses against this organism. Adaptive Th1 response is not sufficient to clear this organism and, as a result, the infection persists."

"Insufficient adaptive immunity can be explained by poor activation of Toll-like receptors, suppressive effects of bacterial factors, and induction of regulatory T-cell responses. Significant progress in the understanding of innate and adaptive immunity against H....


Source: Cancer Weekly (2008-09-23)

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