Cancer Weekly
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Cancer Gene Therapy
Investigators at College of Medicine zero in on cancer gene therapy
September 23rd, 2008
Current study results from the report, 'Expanding the roles for pregnane X receptor in cancer: proliferation and drug resistance in ovarian cancer,' have been published. "We examined the presence of the pregnane X receptor (PXR) and its effects on ovarian cancer cells after activation by its cognate ligand. SKOV-3 and OVCAR-8 ovarian carcinoma cells were analyzed for expression of PXR by quantitative reverse transcription-PCR and Western blot," scientists in the United States report. "Human ovarian cancer tissue was also analyzed for PXR expression by immunochemistry. Ligand (agonist)-induced PXR target genes were analyzed in SKOV-3 cells by quantitative reverse...
Source: Cancer Weekly (2008-09-23)
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