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Cancer Gene Therapy
Research on cancer gene therapy detailed by J. Briese and co-authors
September 23rd, 2008
Data detailed in 'Correlations between reduced expression of the metastasis suppressor gene KAI-1 and accumulation of p53 in uterine carcinomas and sarcomas' have been presented. According to a study from Hamburg, Germany, "Kangai (KAI)-1 (CD82) is a metastasis suppressor gene, which belongs to the family of tetraspanin proteins. A loss of KAI-1 expression is associated with the advanced stages of many human malignancies." "The present study was designed to investigate the expression pattern of KAI-1 in the normal endometrium and uterine tumors and to correlate it with the expression of tumor suppressor protein p53. KAI-1 could be found in the normal endometrium...
Source: Cancer Weekly (2008-09-23)
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