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Cancer Weekly

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Cancer Gene Therapy



Scientists at College of Medicine describe research in cancer gene therapy



September 23rd, 2008

Scientists discuss in 'In vitro susceptibility to anticancer agents of the human KB carcinoma cell line transfected with COX-2 cDNA' new findings in cancer gene therapy. "In order to investigate the malignant phenotype of cyclooxygenase (COX)-2 overexpressing cancer cells, a human epidermoid KB carcinoma cell line minimally expressing COX-2 protein was transfected with human COX-2 cDNA. In this study, we used a COX-2 transfected clone KB/COX-2 and a neomycin-transfected clone KB/neo as the control," scientists writing in the journal Oncology Reports report.

"When we examined the susceptibility to anticancer agents, there was no difference between these two clones...


Source: Cancer Weekly (2008-09-23)

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