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Cancer Weekly

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Cancer Vaccines



Data on cancer vaccines described by researchers at Chittaranjan National Cancer Institute



September 23rd, 2008

Investigators publish new data in the report 'Neem leaf glycoprotein helps to generate carcinoembryonic antigen specific anti-tumor immune responses utilizing macrophage-mediated antigen presentation.' "In an objective to generate effective carcinoembryonic antigen (CEA) specific anti-tumor immune response in Swiss mice, CEA was presented using macrophages with adjuvant help from neem leaf glycoprotein (NLGP). Such vaccination generates significantly higher antibody (IgG2a) and T cell response than immunization protocol without NLGP," scientists in Kolkata, India report.

"NLGP controls the function of both B cells and macrophages by altering the expressions of various...


Source: Cancer Weekly (2008-09-23)

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