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Cancer Weekly

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Cancer Vaccines Immunology



Scientists at University of Tubingen, Department of Internal Medicine II describe research in cancer vaccines immunology



September 23rd, 2008

Research findings, 'Generation of antigen-specific CTL responses using RGS1 mRNA transfected dendritic cells,' are discussed in a new report. "Advances in tumor immunology and Identification of tumor-associated antigens (TAAs) provide a basis for the development of novel immunotherapies to treat malignant diseases. In order to identify novel TAAs, we performed comparative microarray analysis of (heterogeneous) tissues and found regulator of G protein-signaling 1 (RGS1) extensively up-regulated in renal cell carcinoma (RCC) tissues," investigators in Tubingen, Germany report.

"To examine the possible function of this molecule as a novel, broadly applicable TAA, synthetic...


Source: Cancer Weekly (2008-09-23)

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