Xenotransplantion
Research from University Medical Center broadens understanding of xenotransplantion
Published in Cancer Weekly, September 23rd, 2008
According to a study from Hamburg, Germany, "Our aim was to use PET/MRI to evaluate and compare the uptake of F-18-FDG, 3-deoxy-3-F-18-fluorothymidine (F-18-FLT), and F-18-fluorethylcholine (F-18-FEC) in human pancreatic tumor cell lines after xenotransplantation into SCID mice and to correlate tumor uptake with gene expression of membrane transporters and rate-limiting enzymes for tracer uptake and tracer retention. Four weeks after orthotopic inoculation of human pancreatic carcinoma cells (PancTul, Colo357, and BxPC3) into SCID mice, combined imaging was performed with a small-animal PET scanner and a 3-T MRI scanner using a dedicated mouse coil."
"Tumor-to-liver...
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Source: Cancer Weekly (2008-09-23)
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