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Cancer Weekly

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DNA Research



Data on DNA research discussed by investigators at University of New Mexico, Cancer Research and Treatment Center



September 30th, 2008

New research, 'Expression levels of the human DNA repair protein metnase influence lentiviral genomic integration,' is the subject of a report. According to recent research published in the journal Biochimie, "We recently identified a Transposase domain protein called Metnase, which assists in repairing DNA double-strand breaks (DSB) via non-homologous end-joining (NHEJ), and is important for foreign DNA integration into a host cell genome. Since integration is essential for productive lentiviral infection we examined whether Metnase expression levels could have an influence on lentiviral genomic integration."

"Using cells stably transduced to either over-or...


Source: Cancer Weekly (2008-09-30)

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