Cancer Weekly
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Breast Cancer
Data on breast cancer detailed by R.L. Milne and co-authors
September 30th, 2008
According to recent research from Madrid, Spain, "A polygenic model has been proposed to explain the bulk of the genetic component of breast cancer aetiology and this is probably to include both main effects and interactions between multiple loci. However, the power to detect the interactions using traditional analytical methods is very limited for most studies." "Multifactor dimensionality reduction (MDR) has been suggested to have increased power to detect interactions and is increasing being used in published studies. We applied MDR to a two-stage case-control breast cancer study conducted in Spain and Finland. In the stage 1 Spanish study of 864 cases and 845...
Source: Cancer Weekly (2008-09-30)
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