Cancer Weekly
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Cancer Gene Therapy
Research reports from Translational Genomics Research Institute provide new insights into cancer gene therapy
October 7th, 2008
Current study results from the report, 'Gene expression profiling-based identification of cell-surface targets for developing multimeric ligands in pancreatic cancer,' have been published. According to recent research published in the journal Molecular Cancer Therapeutics, "Multimeric ligands are ligands that contain multiple binding domains that simultaneously target multiple cell-surface proteins. Due to cooperative binding, multimeric ligands can have high avidity for cells (tumor) expressing all targeting proteins and only show minimal binding to cells (normal tissues) expressing none or only some of the targets." "Identifying combinations of targets that...
Source: Cancer Weekly (2008-10-07)
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