Cancer Gene Therapy

Studies from Kyoto University in the area of cancer gene therapy published

Published in Cancer Weekly, October 7th, 2008

Research findings, 'Administration of PLK-1 small interfering RNA with atelocollagen prevents the growth of liver metastases of lung cancer,' are discussed in a new report. "Liver metastasis is one of the most important prognostic factors in lung cancer patients. However, current therapies are not sufficient," researchers in Kyoto, Japan report.

"RNA interference provides us a powerful and promising approach for treating human diseases including cancers. Herein, we investigated the in vitro effects of PLK-1 small interfering RNA (siRNA) on human lung cancer cell lines and the in vivo usage of PLK-1 siRNA with atelocollagen as a drug delivery system in a murine liver...

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Source: Cancer Weekly (2008-10-07)

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