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Cancer Weekly

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Life Sciences



Mount Sinai School of Medicine publishes research in life sciences



October 7th, 2008

Research findings, 'The administration of IL-12/GM-CSF and Ig-4-1BB ligand markedly decreases murine floor of mouth squamous cell cancer,' are discussed in a new report. According to a study from the United States, "To assess immune-based gene therapy in a murine floor of mouth (FOM) squamous cell carcinoma (SCC) model. In vitro and in vivo testing of immune therapy for SCC."

"Multiple SCC lines were infected by using advRSV-interleukin-12 (IL-12) and advCMV-interleukin-12/granulocyte macrophage colony-stimulating factor (IL-12/GM-CSF) and monitored for production of IL-12 and GM-CSF. Intratumoral injections of viral vectors were administered with systemic Ig-4-1BB...


Source: Cancer Weekly (2008-10-07)

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