Cancer Weekly
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Cancer Gene Therapy
Studies in the area of cancer gene therapy reported from P. Yu and co-researchers
October 7th, 2008
"Metastatic diseases cause the majority of morbidity and mortality of cancer patients. Established tumors form both physical and immunological barriers to limit immune detection and destruction," scientists in the United States report. "Current immunotherapy of vaccination and adoptive transfer shows limited effect at least in part due to the existing barriers in the tumors and depending on the knowledge of tumor antigens. Tumor necrosis factor (TNF) superfamily (TNFSF) member 14 (TNFSF14) LIGHT interacts with stromal cells, dendritic cells (DCs), NK cells, naive and activated T cells and tumor cells inside the tumor tissues via its two functional receptors, HVEM and...
Source: Cancer Weekly (2008-10-07)
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