Cancer Weekly
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Breast Cancer
New breast cancer study results reported from M.W. Helms et al
October 7th, 2008
According to a study from Hamburg, Germany, "Gains of chromosomes 7p and 8q are associated with poor prognosis among oestrogen receptor-positive ( ER+) stage I/II breast cancer. To identify transcriptional changes associated with this breast cancer subtype, we applied suppression subtractive hybridisation method to analyse differentially expressed genes among six breast tumours with and without chromosomal 7p and 8q gains." "Identified mRNAs were validated by real-time RT-PCR in tissue samples obtained from 186 patients with stage I/II breast cancer. Advanced statistical methods were applied to identify associations of mRNA expression with distant metastasis-free...
Source: Cancer Weekly (2008-10-07)
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