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Germ Cell Cancer Gene Therapy
Research from University Hospital, Department of Oncology provides new data on germ cell cancer gene therapy
October 14th, 2008
Investigators publish new data in the report 'Comparative proteome, transcriptome, and genome analysis of a gonadal and an extragonadal germ cell tumor cell line.' "Whereas clinical differences between testicular and extragonadal germ cell tumors (GCT), like reduced cisplatin sensitivity of extragonadal tumors, are well-established, little is known about underlying tumor biology. A combined approach using global proteome analysis and RT-PCR to assess mRNA levels of selected proteins on the one hand, and array comparative genomic hybridization (array-CGH), on the other hand, was used to compare two germ cell tumor (GCT) cell lines showing embryonal carcinoma histology, one of testicular,...
Source: Cancer Weekly (2008-10-14)
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