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Glioblastoma Gene Therapy
New glioblastoma gene therapy research has been reported by scientists at Virginia Commonwealth University
October 14th, 2008
Fresh data on glioblastoma are presented in the report 'Sphingosine-1-phosphate and interleukin-1 independently regulate plasminogen activator inhibitor-1 and urokinase-type plasminogen activator receptor expression in glioblastoma cells: implications for invasiveness.' "Glioblastoma multiforme is an invasive primary brain tumor, which evades the current standard treatments. The invasion of glioblastoma cells into healthy brain tissue partly depends on the proteolytic and nonproteolytic activities of the plasminogen activator system proteins, including the urokinase-type plasminogen activator (uPA), plasminogen activator inhibitor 1 (PAI-1), and a receptor for uPA (uPAR)," scientists in...
Source: Cancer Weekly (2008-10-14)
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