Cancer Weekly
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Angiogenesis
Study findings on angiogenesis are outlined in reports from Wayne State University, Medical Department
October 14th, 2008
"Bcl-2 family of proteins plays critical roles in human cancers, including pancreatic cancer, suggesting that the discovery of specific agents targeting Bcl-2 family proteins would be extremely valuable for pancreatic cancer therapy. We have previously reported the synthesis and characterization of TW-37, which seems to be a negative regulator of Bcl-2," scientists writing in the International Journal of Cancer report. "In this investigation, we tested our hypothesis whether TW-37 could be an effective inhibitor of cell growth, invasion and angiogenesis in pancreatic cancer cells. Using multiple cellular and molecular approaches such as MTT assay, apoptosis...
Source: Cancer Weekly (2008-10-14)
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