Cancer Weekly
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Cancer Vaccines
Data on cancer vaccines reported by S.W. Howland and co-researchers
October 14th, 2008
"Saccharomlyces cerevisiae Stimulates dendritic cells (DCs) and represents a promising candidate for cancer vaccine development. Effective cross-presentation of antigen delivered to DCs is necessary for Successful induction of cellular immunity," scientists writing in the Journal of Immunotherapy report. "Here, we present a yeast-based vaccine approach that is independent of yeast's ability to express the chosen antigen, which is instead produced separately and conjugated to the yeast cell wall. The conjugation method is site-specific (based on the SNAP-tag) and designed to facilitate antigen release in the DC phagosome and Subsequent translocation for...
Source: Cancer Weekly (2008-10-14)
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