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Cancer Weekly

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Cancer Gene Therapy



Tokyo Medical University, Department of Urology details research in cancer gene therapy



October 21st, 2008

New investigation results, 'Effects of a KiSS-1 peptide, a metastasis suppressor gene, on the invasive ability of renal cell carcinoma cells through a modulation of a matrix metalloproteinase 2 expression,' are detailed in a study published in Life Sciences. "Although effects of a metastasis suppressor gene, KiSS-1, have been postulated to be mediated by its receptor, hOT7T175, the mechanism of such effects remains unknown. This study was designed to evaluate the mechanism of how KiSS-1 works and to assess effects of a synthesized truncated KiSS-1 protein on the invasive ability of renal cell carcinoma (RCC) cells," investigators in Tokyo, Japan report.

"Four RCC...


Source: Cancer Weekly (2008-10-21)

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