Cancer Weekly
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Cancer Weekly
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Cancer Vaccines
Researchers from Southampton University, Cancer Sciences Division report on findings in cancer vaccines
October 21st, 2008
Researchers detail in 'Optimising anti-tumour CD8 T-cell responses using combinations of immunomodulatory antibodies,' new data in cancer. "Immunostimulatory mAb as vaccine adjuvants for the treatment of cancer hold considerable potential for boosting weak responses when used against immunogenic tumours, or in combination with various other vaccines. We now show that when administered with OVA, the combination of anti-4-1BB mAb with anti-CD40, anti-OX40 or anti-CD25 resulted in a fourfold enhancement in the antigen-specific T-cell response compared with anti-4-1BB mAb alone, with a similar enhancement in memory responses following rechallenge with OVA," scientists in Southampton, the...
Source: Cancer Weekly (2008-10-21)
|
