Cancer Weekly
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Cancer Vaccines
Reports summarize cancer vaccines research from Q. Zhou and co-authors
October 28th, 2008
According to a study from Guangzhou, People's Republic of China, "XAGE-1b is regarded as one of the most immunogenic antigens and the most promising targets for lung adenocarcinoma immunotherapy. In this study, we sought to determine whether monocyte-derived dendritic cells (DCs) pulsed with purified full-length XAGE-1b could induce specific cytotoxic T lymphocytes (CTLs) against tumour cells from patients with non-small cell lung cancer (NSCLC) in vitro." "XAGE-1b mRNA expression was examined in primary cultures of lung cancer cells and normal lung epithelial cells established from fresh tissues surgically resected from 30 patients with NSCLC using reverse...
Source: Cancer Weekly (2008-10-28)
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