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Cancer Weekly

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Cancer Gene Therapy



Reports summarize cancer gene therapy study results from Soochow University



October 28th, 2008

According to a study from Suzhou, People's Republic of China, "Interleukin-24 (IL-24) has been shown to be a tumor-suppressor gene and the protein product found to be constitutively expressed by melanocytes, nerve cells, and some primary melanomas. The potential effect of adenovirus (AdV)-mediated IL-24 gene therapy was explored on human pancreatic carcinoma by using a pancreatic carcinoma cell line, patu8988."

"A recombinant adenovirus, AdVGFP/IL-24, expressing the marker, green fluorescent protein (GFP), and the tumor-suppressor gene, IL-24, was constructed. Ad-VGFP/IL-24 treatment of pancreatic carcinoma cells in vitro significantly induced pancreatic carcinoma cell...


Source: Cancer Weekly (2008-10-28)

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