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Adverse Drug Reactions
Studies from F. Russo et al in the area of adverse drug reactions described
October 28th, 2008
According to recent research from Sesto Fiorentino, Italy, "The main objective of this study was to evaluate the safety of second-line pemetrexed in Stage IIIB or IV NSCLC. Overall, 95 patients received pemetrexed 500 mg/m(2) i.v. over Day 1 of a 21-day cycle." "Patients also received oral dexamethasone, oral folic acid and i.m. vitamin B12 supplementation to reduce toxicity. NCI CTC 2.0 was used to rate toxicity. All the adverse events were graded in terms of severity and relation to study treatment. Dose was reduced in case of toxicity and treatment was delayed for up to 42 days from Day 1 of any cycle to allow recovering from study drug-related toxicities. Tumor...
Source: Cancer Weekly (2008-10-28)
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