Cancer Weekly
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Angiogenesis
Reports from University of Tromso, Medical Department add new data to research in angiogenesis
October 28th, 2008
According to a study from Norway, "In tumor angiogenesis there is a complex interplay between endothelial. stromal, and tumor cells (neoplastic epithelial cells). Platelet-derived growth factors (PDGFs) and receptors (PDGFRs) are pivotal in this interaction, and important targets in novel antiangiogenic therapies." "This Study investigates the prognostic impact of these molecular markers in tumor cells and tumor stroma of resected non-small cell lung cancer (NSCLC) tumors. Tumor tissue samples from 335 resected patients with stage I to IIIA NSCLC were obtained and tissue microarrays were constructed from duplicate cores Of tumor cells and tumor-related stroma from each...
Source: Cancer Weekly (2008-10-28)
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