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Cancer Weekly

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Cancer Vaccines



Studies from M. Barve and colleagues reveal new findings on cancer vaccines



November 4th, 2008

" Generation of broad cytotoxic T-lymphocyte responses against multiple epitopes and tumor-associated antigens (TAAs) may provide effective immunotherapy in patients with cancer. We evaluated a single-vial peptide vaccine consisting of nine HLA-A2 supertype-binding epitopes (two native and seven analog epitopes modified for optimal HLA binding or T-cell receptor stimulation) covering five TAAs and the universal helper pan-DR epitope, formulated as a stable emulsion with incomplete Freund's adjuvant (Montanide ISA 51; Seppic SA, Paris, France)," scientists in the United States report.

"The clinical efficacy, safety, and multiepitope immunogenicity of IDM-2101 was...


Source: Cancer Weekly (2008-11-04)

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