Cancer Weekly
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Cancer Vaccines
Studies from M. Barve and colleagues reveal new findings on cancer vaccines
November 4th, 2008
" Generation of broad cytotoxic T-lymphocyte responses against multiple epitopes and tumor-associated antigens (TAAs) may provide effective immunotherapy in patients with cancer. We evaluated a single-vial peptide vaccine consisting of nine HLA-A2 supertype-binding epitopes (two native and seven analog epitopes modified for optimal HLA binding or T-cell receptor stimulation) covering five TAAs and the universal helper pan-DR epitope, formulated as a stable emulsion with incomplete Freund's adjuvant (Montanide ISA 51; Seppic SA, Paris, France)," scientists in the United States report. "The clinical efficacy, safety, and multiepitope immunogenicity of IDM-2101 was...
Source: Cancer Weekly (2008-11-04)
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