Cancer Weekly
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Vaccines
Research from McMaster University in the area of vaccines published
November 4th, 2008
"Biomaterials are promising candidate adjuvants to enhance vaccine efficacy. Through adjuvant design, we can broaden the use of vaccines to diseases such as AIDS, malaria, and cancer," scientists in Hamilton, Canada report. "This review addresses the fundamentals of vaccine and adjuvant function in order to determine guidelines for adjuvant design, including aspects of the vaccine such as disease target, antigen formulation, and delivery route. An ideal biomaterial adjuvant will perform three functions. (1) It will deliver the antigen selectively to dendritic cells. This has been accomplished through release of chemokines or cytokines, use of antidendritic cell...
Source: Cancer Weekly (2008-11-04)
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