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Cancer Weekly

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Adenocarcinoma



Researchers at INSERM have published new data on adenocarcinoma



November 4th, 2008

According to recent research from Lyon, France, "The actin-binding protein gelsolin is involved in cell motility via the regulation of actin cytoskeleton, and its expression is modified in several human cancers. However, the potential implication of this protein in colorectal carcinogenesis is debated."

"By using immumohistochemistry, we studied gelsolin expression in 69 cases of colon adenocarcinomas and in 72 lesions representative of the different stages of colonic tumorigenesis. In addition, we performed Northern blot analysis of gelsolin messenger RNA in 12 paired samples of human colon cancer and normal corresponding mucosa. Gelsolin protein and messenger RNA...


Source: Cancer Weekly (2008-11-04)

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