Cancer Weekly
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Adenocarcinoma
Studies conducted at H.M. Horlings et al on adenocarcinoma recently published
November 4th, 2008
According to a study from Netherlands, " Patients with adenocarcinoma of unknown primary origin (ACUP) constitute approximately 4% of all malignancies. For effective treatment of these patients, it is considered optimal to identify the primary tumor origins." "Currently, the success rate of the diagnostic work-up is only 20% to 30%. Our goal was to evaluate the contribution of gene expression profiling for routine clinical practice in patients with ACUP. Patients and Methods Formalin-fixed, paraffin-embedded (FFPE) samples were obtained from 84 patients with a known primary adenocarcinoma and from 38 patients with ACUP. An extensive immunohistochemical panel classified...
Source: Cancer Weekly (2008-11-04)
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